WHO in September added GLP-1 drugs as a diabetes treatment to its list of essential medicines, but stopped short of adding them for obesity alone. When reporting please provide as much information as possible, including information about medical history, any concomitant medication, onset, treatment dates, product brand name, details of your suspicion of inappropriate use or misuse and include all relevant patient details including weight or BMI, and if possible, where the product was obtained (i.e. NHS prescription, private prescription, including online prescriptions, or illegitimate supplier). Cardiovascular protective mechanisms are outlined, including improvements in lipid metabolism, reductions in blood pressure, enhanced endothelial nitric oxide activity, suppression of macrophage inflammation, decreased foam-cell formation, and stabilization of atherosclerotic plaques. Recently, the European Union’s agency that regulates medicine safety listed NAION as a "very rare" side effect of semaglutide - the active ingredient in some of the most popular weight loss drugs including Novo Nordisk’s Ozempic and Wegovy. GLP-1 medications can be an effective tool for managing diabetes and supporting weight loss. "The patients taking ColonBroom GLP-1 RA medications report that the ‘food noise’ - the constant thinking about food - is quieter," Ali said.