This is because overloading the muscle cell with glycogen causes ache and may also lead to death of individual muscle cells. Blood work often exhibits increased muscle enzyme activity in horses with Type 1 PSSM, usually even at relaxation. The danger of a glycogen overloading arises when affected horses devour lots of simply digestible carbohydrates like starch or sugar, leading to a rise in blood sugar levels, and the muscle cells absorb some of the excess blood sugar and store it in glycogen. Also problematic for affected horses are sudden, high performance demands - as a result of even if part of their glycogen shops can't be damaged down normally, this does not apply to the whole glycogen of the muscle. If strenuous muscular effort causes a depletion of those usually depletable stores, there will probably be elevated formation of latest glycogen throughout the regeneration phase, with abnormal glycogen forming once more and overloading the muscle cells. There is now a easy genetic test to find out whether a horse suffers from Type 1 PSSM.

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